Meaning of 'tophus' in Yoruba is: tophus

tophus: tophus

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Tophus(1)

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(1) If histopathology of a tophus or synovial biopsy suggests gout, fine-needle aspiration may be an alternative for crystal identification and subsequent definitive diagnosis.(2) Less commonly, a septic arthritis of the knee or the big toe can occur in association with gout, particularly when a tophus has ulcerated and become secondarily infected.(3) One swallow does not make a summer, but one tophus makes gout and one crescent malaria.(4) Four years later, he obtained uric acid from a gouty tophus .(5) The slides stained with HE and our method were examined with a light microscope for the presence of urate crystals and diagnostic histologic features of gouty tophus .(6) Diagnosis is by removing fluid from an affected joint or tophus and identifying urate crystals under a polarized-light microscope.(7) Only a minority of patients with hyperuricemia develops tophi and gouty arthritis.(8) Chalky deposits called tophi may appear under the skin around joints and in the cartilage of the ears.(9) Joint damage in hyperuricemia causes classical attacks of gout but tophi may also develop in cartilage, tendons and other tissues.(10) Crystal deposits may also build up under the skin around the joints and behind the ears, causing small lumps known as tophi and, in a few cases, in the kidneys.(11) Definite diagnosis can be made by demonstration of the presence of monosodium urate crystals within synovial leukocytes or in material derived from tophi under polarizing microscopy.(12) Patients with long-standing gout may have tophi over the olecranon prominence, first metatarsal joints, or pinnae.